Mary was flesh and blood and Jesus was her son, flesh, blood, and connected with her people.  We think very highly of Mary through the window of sacred history, but others saw the designation of Jesus as her son to be a justification for derision. It was not her reputation for having conceived Him out of wedlock at this point that framed their curses. That would come up at some point, but this was subtler. They accused Him of being common and familiar. They knew Him and His brothers and their familiarity bred contempt.

He was common and He was uncommon. As the son of Mary, He had history and culture, family and traditions. He was given the gifts of language, nuance, familial customs, memories, and relationships, but He was always, also the Son of God and that reality was easily obscured to those who knew Him best as a carpenter.

We must be careful not to allow familiarity to obscure holiness to our view. The ordinary may not be so ordinary at all. Our familiarity with the things of God can be a liability if we forget to seek the sacred amidst the profane.